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fbp [2017-8-11 16:0:3]
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fbp [2017-8-11 16:0:3]

fructose-1,6-bisphosphatase, involved in gluconeogenesis
locus
BSU40190
pI
5.60
mw
77.80 kDa
protein length
671 aa Sequence Blast
gene length
2013 bp Sequence Blast
function
gluconeogenesis
product
fructose-1,6-bisphosphatase
essential
no
ec
3.1.3.11
synonyms
fdp, yydE
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.1|Carbon core metabolism] → [category|SW 2.2.1.2|Gluconeogenesis]

    • Gene

    Coordinates
    4,128,029 → 4,130,044

    The protein

    Catalyzed reaction/ biological activity

  • D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate (according to Swiss-Prot)

    • Protein family

  • FBPase class 3 family (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|79DD9B2E2EBB4646327AFC2148CE040823DE89D3|fbp]
    description
    [pubmed|22383849,9696785]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [pubmed|9696785], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
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    Biological materials

    Mutant

  • MGNA-B811 (yydE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1810 NBRP B. subtilis, Japan]

    • References

  • 6257649,221467,9696785,24571712